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24709a Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR
26789Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
26790Structural Basis for 3-deoxy-cdca Binding and Activation of FXR
63159Structure of Human FXR in Complex With Mfa-1 and CO- Activator Peptide
66041FXR With Src1 and Gw4064
66042FXR With Src1 and Gsk8062
78874Discovery of Xl335, a Highly Potent, Selective and Orally- Active Agonist of the Farnesoid X Receptor (Fxr)
70843Identification of an N-oxide Pyridine Gw4064 Analogue as a Potent FXR Agonist
75146Isoxazole Ligand Bound to Farnesoid X Receptor (Fxr)
75477FXR With Src1 and Gsk826
75478FXR With Src1 and Gsk088
80507Complex Structure of FXR Ligand-binding Domain With a Tetrahydroazepinoindole Compound
87622Crystal Structure of Human FXR in Complex With 2-(4-chlorophenyl)-1- [(1s)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1h-benzimidazole- 6-carboxylic Acid
87623Crystal Structure of Human FXR in Complex With (2s)-2-[2-(4- Chlorophenyl)-1h-benzimidazol-1-yl]-n,2-dicyclohexylethanamide
88071Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)-3-methylbenzoic Acid
88072Crystal Structure of Human FXR in Complex With (2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2-cyclohexyl-n-(2- Methylphenyl)ethanamide
88073Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)-3-fluorobenzoic Acid
88077Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)benzoic Acid
88078Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)-3,5-difluorobenzoic Acid